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Savi is an accomplished professional who is working toward the next phase in her life, both professionally and personally. At the same time that she and her husband, Harry, are attempting to start a family of their own, Savi is vying for the position of partner at her law firm. She is also working toward becoming a mother. Josselyn, the younger sister of Savi, is a free-spirit who is prone to irrational behavior. She is constantly partying, engaging in a string of casual relationships, and relies heavily on Savi for guidance. Their mutual best friend April, who is also a new widow and a mother of two, is in the process of reconstructing her life after a catastrophe and learning how to move on with the love and counsel of her closest girlfriends. And the ladies' old friend Karen, who is also a successful therapist and has her own thriving practice, gets back in touch with them after realizing that her involvement in a troubled relationship with a patient has gone too far.